CELLULAR ORIGIN OF RHEUMATOID FACTOR
نویسندگان
چکیده
منابع مشابه
Cellular Origin of Rheumatoid Factor
Fluorescein-labelled aggregated human gamma-globulin was found to react in precipitin-type tests with serums of individuals with rheumatoid arthritis. This reagent was also highly reactive and specific for the localization of rheumatoid factor in frozen sections of synovial membranes, lymph nodes, and subcutaneous nodules. In synovial membranes from patients with active rheumatoid arthritis, rh...
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The rheumatoid factor, a group of unusual macroglobulins, is demonstrable in the serum of the majori ty of patients with rheumatoid arthritis and in a relatively small proportion of patients with other diseases (1). The presence of this factor can be demonstrated by its reaction with human v-globulin (Cohn fraction I I ) in such serological procedures as the tanned sheep cell agglutination (2) ...
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15 صفحه اولComparative Measurement of Rheumatoid Factor in Serum and Synovial Fluid of Rheumatoid Arthritis Patients by ELISA and Latex-Agglutination Test
Rheumatoid factors (RF) are autoantibodies with specificity for the Fc portion of human IgG. Production of RF is a characteristic feature of rheumatoid arthritis (RA) and is detectable in high titer in about 90% of these patients. In this study, we measured total IgM, IgA, IgMRF and IgARF in serum and synovial fluid of 45 RA patients by ELISA and the results were compared with those obtained b...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1959
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.110.6.875